Pesquisa sobre: INTERFERON REGULATORY FACTOR-3 
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Descritor Inglês:   Interferon Regulatory Factor-3 
Descritor Espanhol:   Factor 3 Regulador del Interferón 
Descritor Português:   Fator Regulador 3 de Interferon 
Sinônimos Inglês:   IRF-3 Transcription Factor  
Categoria:   D12.644.360.024.302.374
D12.776.157.057.050.374
D12.776.260.504.374
D12.776.476.024.385.374
D12.776.744.562
D12.776.930.332.374
Definição Inglês:   An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription. 
Nota Histórica Inglês:   2006(1996) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   50777 
Identificador Único:   D050838 

Ocorrência na BVS:
 

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